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G Protein-Coupled Inwardly-Rectifying Potassium Channels (GIRK channels) are channels found in the brain that play a crucial role ingirk the inhibitory effects of neurotransmitters.

G-protein-gated inwardly rectifying K + (GIRK) channels play a key role in maintaining resting membrane potential, cell excitability and inhibitory neurotransmission.

G protein-coupled inwardly rectifying potassigirkum (GIRK) channels can be activated or inhibited by different classes of receptors, suggesting a role for G proteins in determining signaling specificity.

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